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Hydroquinone topical

Generic name: hydroquinone topical [ HYE-droe-KWIN-one-TOP-ik-al ]
Brand names: EpiQuin Micro, Kaxm, Keido, Kexm, Kutea, ... show all 40 brands
Dosage forms: topical cream (2%; 4%), topical emulsion (4%; 6%; 8%)
Drug class: Topical depigmenting agents

Medically reviewed by Drugs.com on Jul 31, 2023. Written by Cerner Multum.

What is hydroquinone topical?

Hydroquinone topical (for the skin) is used to lighten areas of darkened skin such as freckles, age spots, melasma (sun damage), or chloasma (darkened skin caused by hormonal changes).

Hydroquinone topical may also be used for purposes not listed in this medication guide.

Hydroquinone topical side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Hydroquinone topical may cause serious side effects. Stop using hydroquinone topical and call your doctor at once if you have:

Common side effects of hydroquinone topical may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use hydroquinone topical if you are allergic to hydroquinone or peroxide.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Do not give this medicine to anyone under 12 years old without medical advice.

How should I use hydroquinone topical?

Use exactly as directed on the label, or as prescribed by your doctor.

Hydroquinone topical is usually applied each morning and at bedtime. Follow your doctor's dosing instructions very carefully.

Do not take by mouth. Topical medicine is for use only on the skin.

Before you start using hydroquinone topical, use a "test dose" to see if you have an allergic reaction to this medicine. Apply a very small amount of the medicine to a small area of healthy skin, and check the area within 24 hours. If there is no reaction other than minor redness, begin using the full prescribed amount of the medicine.

Wash your hands before and after applying this medicine, unless you are using it to treat the skin on your hands.

Apply this medicine only to the affected skin areas that need to be lightened. Try not to get any medicine on the skin around these areas.

Do not use hydroquinone topical on open wounds or on sunburned, windburned, dry, chapped, or irritated skin.

Call your doctor if your symptoms do not improve after 2 months, or if your condition gets worse.

Store at room temperature away from moisture and heat. Keep the container tightly closed when not in use.

Hydroquinone topical dosing information

Usual Adult Dose for Dermatological Disorders:

Apply to affected areas 2 times a day in the morning and at bedtime or as directed; if no improvement is seen after 2 months of therapy, discontinue use

Comments:
-Rub in well.

Use: For the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation

Usual Pediatric Dose for Dermatological Disorders:

12 years and older:
Apply to affected areas 2 times a day in the morning and at bedtime or as directed; if no improvement is seen after 2 months of therapy, discontinue use

Comments:
-Rub in well.

Use: For the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation

What happens if I miss a dose?

Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.

What happens if I overdose?

An overdose of hydroquinone topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

What should I avoid while using hydroquinone topical?

Avoid getting hydroquinone topical in your eyes.

Avoid getting this medicine on your lips or inside your nose or mouth. Hydroquinone may cause numbness in these areas.

Avoid exposure to sunlight or tanning beds. Hydroquinone topical can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Some hydroquinone products may contain sunscreen. Check the medicine label or ask your doctor to be sure.

Hydroquinone topical may make your skin more sensitive to weather extremes such as cold and wind. Protect your skin with clothing and use a moisturizing lotion as needed.

Using hydroquinone topical together with benzoyl peroxide, hydrogen peroxide, or other peroxide products may stain your skin. This staining can usually be removed with soap and water.

Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.

What other drugs will affect hydroquinone topical?

Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.